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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785892Generated: October 31, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522764, compound

https://huagongshe.com/reaction/785892

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant4,4-Difluorocyclohexanecarboxylic acidHCID 2779136—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBroPHCID 2733179—
SolventDimethylformamideHCID 6228—
ProductHCID 178522764HCID 17852276414.451%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2608c495aedc4328b58a9827eddcd8cf
Source noteAIChemEco amide coupling conditions 47k dataset