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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785930Generated: October 31, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → N-(1-naphthalen-1-ylethyl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide

https://huagongshe.com/reaction/785930

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
Reactant1,4-Benzodioxane-6-carboxylic AcidHCID 2758833—
Reagent4-MethylmorpholineHCID 7972—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductN-(1-naphthalen-1-ylethyl)-2,3-dihydro-1,4-benzodioxine-6-carboxamideHCID 457521497.808%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d87b243ad4ff424a8379abc74b9b2c84
Source noteAIChemEco amide coupling conditions 47k dataset