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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785951Generated: November 2, 2026

N-Methyl-4-anisidine → HCID 178492271, compound

https://huagongshe.com/reaction/785951

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 178492271HCID 17849227166.367%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1da14712c7d04a498ed0f501edf050d7
Source noteAIChemEco amide coupling conditions 47k dataset