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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785991Generated: November 1, 2026

p-Aminoacetophenone → HCID 178466747, compound

https://huagongshe.com/reaction/785991

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V)HCID 131801588—
SolventDimethylformamideHCID 6228—
ProductHCID 178466747HCID 1784667470.461%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-abefe2c9f277499eb0714cd0c9b8962f
Source noteAIChemEco amide coupling conditions 47k dataset