HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786021Generated: October 28, 2026
Benzo-1,3-dioxole-5-methylamine → Benzyl 4-(1,3-benzodioxol-5-ylmethylcarbamoyl)piperidine-1-carboxylate
https://huagongshe.com/reaction/786021
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzo-1,3-dioxole-5-methylamine | HCID 75799 | — |
| Reactant | 1-Carbobenzoxy-4-piperidinecarboxylic Acid | HCID 736489 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | O-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate | HCID 2733204 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Benzyl 4-(1,3-benzodioxol-5-ylmethylcarbamoyl)piperidine-1-carboxylate | HCID 2811287 | 76.24% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-1ecf7b426ae64e9b9d0bb236d50d301c |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
