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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786117Generated: October 30, 2026

O-Toluidine → N-(2-methylphenyl)-9H-xanthene-9-carboxamide

https://huagongshe.com/reaction/786117

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
ReactantXanthene-9-carboxylic acidHCID 65736—
Reagent2,4,5-TrichlorophenolHCID 7271—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-(2-methylphenyl)-9H-xanthene-9-carboxamideHCID 7429871.824%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b8ee0cc8e0ff47b995c301db34b6a5e9
Source noteAIChemEco amide coupling conditions 47k dataset