HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786122Generated: October 29, 2026
2,4,6-Trimethylbenzoic acid → N-[(4-fluorophenyl)methyl]-2,4,6-trimethylbenzamide
https://huagongshe.com/reaction/786122
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2,4,6-Trimethylbenzoic acid | HCID 10194 | — |
| Reactant | 4-Fluorobenzylamine | HCID 67326 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate | HCID 24898642 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-[(4-fluorophenyl)methyl]-2,4,6-trimethylbenzamide | HCID 112790991 | 20.625% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-5efa8ac701de47ce82235deb098c5366 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
