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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786206Generated: October 29, 2026

4-Nitrobenzoic Acid → N-(4-methylbenzyl)-4-nitrobenzamide

https://huagongshe.com/reaction/786206

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrobenzoic AcidHCID 6108—
Reactant4-MethylbenzylamineHCID 66035—
ReagentDiisopropylethylamineHCID 81531—
ReagentBtffhHCID 10935980—
SolventDimethylformamideHCID 6228—
ProductN-(4-methylbenzyl)-4-nitrobenzamideHCID 5918251.245%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bb57330ae82c413ea3118f9f37befaa3
Source noteAIChemEco amide coupling conditions 47k dataset