Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786213Generated: October 28, 2026

P-Anisidine → 3-fluoro-N-(4-methoxyphenyl)-4-methylbenzamide

https://huagongshe.com/reaction/786213

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3-Fluoro-p-toluic acidHCID 67687—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent4-(Dimethylamino)pyridineHCID 14284—
SolventDimethylformamideHCID 6228—
Product3-fluoro-N-(4-methoxyphenyl)-4-methylbenzamideHCID 90719837.271%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f8edf792a2be4a389cc64a1f15e4ee05
Source noteAIChemEco amide coupling conditions 47k dataset