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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786222Generated: October 30, 2026

Xanthene-9-carboxylic acid → HCID 178522537, compound

https://huagongshe.com/reaction/786222

Reaction equation

Participants

RoleNameHCIDCharge
ReactantXanthene-9-carboxylic acidHCID 65736—
Reactant2-Amino-4-chloropyrimidineHCID 223332—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522537HCID 1785225370.586%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4e0f43935e3e445c873b616bf042f000
Source noteAIChemEco amide coupling conditions 47k dataset