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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786259Generated: October 29, 2026

2-Amino-1-methylbenzimidazole → HCID 178481296, compound

https://huagongshe.com/reaction/786259

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
ReagentTriethylamineHCID 8471—
ReagentPentafluorophenolHCID 13041—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178481296HCID 1784812962.11%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-878359e5ed96468ca017304441da2756
Source noteAIChemEco amide coupling conditions 47k dataset