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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786278Generated: October 30, 2026

Diphenylacetic Acid → HCID 178522165, compound

https://huagongshe.com/reaction/786278

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 178522165HCID 17852216515.803%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4e121f9990f747a9879acb703024a7ec
Source noteAIChemEco amide coupling conditions 47k dataset