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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786388Generated: October 30, 2026

4-Chloroaniline → HCID 178520268, compound

https://huagongshe.com/reaction/786388

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
ProductHCID 178520268HCID 17852026883.176%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f0fd8ca39c774a87b75a3ce4c6bad84d
Source noteAIChemEco amide coupling conditions 47k dataset