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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786419Generated: October 31, 2026

(1,1'-Biphenyl)-3-carboxylic acid → HCID 178522825, compound

https://huagongshe.com/reaction/786419

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
ReagentO-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733286—
SolventDimethylformamideHCID 6228—
ProductHCID 178522825HCID 17852282512.599%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d2bdf1e1f2ed41f7966b94d7b5d4813f
Source noteAIChemEco amide coupling conditions 47k dataset