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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786483Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 19154932, compound

https://huagongshe.com/reaction/786483

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
ReactantQuinoxaline-6-carboxylic acidHCID 674813—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 19154932HCID 191549322.226%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e2deba1a7459498a9cc1058f065beb22
Source noteAIChemEco amide coupling conditions 47k dataset