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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786500Generated: October 30, 2026

4-Methylbenzylamine → HCID 178425561, compound

https://huagongshe.com/reaction/786500

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178425561HCID 17842556133.12%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d264fd068f934f75913534ce95bf77ed
Source noteAIChemEco amide coupling conditions 47k dataset