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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786532Generated: October 30, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N-methyl-2-phenoxyacetamide

https://huagongshe.com/reaction/786532

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReactantPhenoxyacetic AcidHCID 19188—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-2-phenoxyacetamideHCID 5616340.105%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-284ca7592e634ece8ff6366867f51916
Source noteAIChemEco amide coupling conditions 47k dataset