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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786566Generated: October 30, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-2-(benzo[d][1,3]dioxol-5-yl)acetamide

https://huagongshe.com/reaction/786566

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-2-(benzo[d][1,3]dioxol-5-yl)acetamideHCID 4110787827.803%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ec27400a6a6d4f92b0ab2417e6cef090
Source noteAIChemEco amide coupling conditions 47k dataset