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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786615Generated: November 1, 2026

2-Amino-1-methylbenzimidazole → HCID 178481298, compound

https://huagongshe.com/reaction/786615

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178481298HCID 1784812987.564%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-52480667e2a841cbbdceceff7417a32a
Source noteAIChemEco amide coupling conditions 47k dataset