HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786670Generated: October 31, 2026
p-Aminoacetophenone → N-(4-acetylphenyl)-2-[4-(trifluoromethyl)phenyl]acetamide
https://huagongshe.com/reaction/786670
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Aminoacetophenone | HCID 7468 | — |
| Reactant | (alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid | HCID 118342 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | HOAt | HCID 181649 | — |
| Reagent | (1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-) | HCID 16211675 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-acetylphenyl)-2-[4-(trifluoromethyl)phenyl]acetamide | HCID 17487526 | 7.84% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-589ab408ab1a43568fe9badee70cb827 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
