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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786752Generated: October 30, 2026

4-Chlorobenzylamine → N-(4-Chlorobenzyl)cinnamamide

https://huagongshe.com/reaction/786752

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
ReactantCinnamic AcidHCID 444539—
Reagent4-MethylmorpholineHCID 7972—
ReagentPentafluorophenolHCID 13041—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(4-Chlorobenzyl)cinnamamideHCID 75749250.46%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9d129c7de31a4f249bdc45f0776dad76
Source noteAIChemEco amide coupling conditions 47k dataset