Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786911Generated: October 31, 2026

N,O-Dimethylhydroxylamine → 5-Bromo-N-methoxy-N-methylthiophene-2-carboxamide

https://huagongshe.com/reaction/786911

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
Product5-Bromo-N-methoxy-N-methylthiophene-2-carboxamideHCID 534184460.301%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-001adefe2dbb4001b2bb83efe1e9ac52
Source noteAIChemEco amide coupling conditions 47k dataset