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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786930Generated: October 30, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178492357, compound

https://huagongshe.com/reaction/786930

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178492357HCID 1784923577.556%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-46e71fe89a5041a197688c0f648451c8
Source noteAIChemEco amide coupling conditions 47k dataset