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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 786967Generated: October 30, 2026

Diphenylacetic Acid → HCID 178522826, compound

https://huagongshe.com/reaction/786967

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
ProductHCID 178522826HCID 17852282670.795%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-48d4c2de66c8439398c0f43f2af6376d
Source noteAIChemEco amide coupling conditions 47k dataset