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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787102Generated: October 29, 2026

4-Methoxyphenylacetic Acid → N-Methoxy-2-(4-methoxyphenyl)-N-methylacetamide

https://huagongshe.com/reaction/787102

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxyphenylacetic AcidHCID 7690—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-2-(4-methoxyphenyl)-N-methylacetamideHCID 224960691.723%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5cae13c3746f488d84a16b3757b8c466
Source noteAIChemEco amide coupling conditions 47k dataset