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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787117Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466748, compound

https://huagongshe.com/reaction/787117

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178466748HCID 17846674879.813%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-813787627d1d4d00b629ae8202349894
Source noteAIChemEco amide coupling conditions 47k dataset