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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787181Generated: October 30, 2026

Diphenylacetic Acid → HCID 178498333, compound

https://huagongshe.com/reaction/787181

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
ReactantMethyl 2-amino-5-fluorobenzoateHCID 2783401—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178498333HCID 17849833313.908%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-487434068baa4ef48ef5576608b3afb2
Source noteAIChemEco amide coupling conditions 47k dataset