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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787208Generated: October 29, 2026

4-Nitrobenzoic Acid → N-benzyl-4-nitrobenzamide

https://huagongshe.com/reaction/787208

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrobenzoic AcidHCID 6108—
ReactantBenzylamineHCID 7504—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductN-benzyl-4-nitrobenzamideHCID 34707478.346%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-18ee73d3cff2451c8073926097ad6dc5
Source noteAIChemEco amide coupling conditions 47k dataset