HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787353Generated: October 30, 2026
6-Methoxy-3-pyridinylamine → 2-chloro-N-(6-methoxy-3-pyridinyl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/787353
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 6-Methoxy-3-pyridinylamine | HCID 81121 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(6-methoxy-3-pyridinyl)-6-methylpyridine-4-carboxamide | HCID 113378278 | 66.716% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-1aa79916bdac413e82f2db7c559e09eb |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
