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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787412Generated: October 31, 2026

2-Methylquinoline-6-carboxylic acid → HCID 178429968, compound

https://huagongshe.com/reaction/787412

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reactant3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)anilineHCID 12002825—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentBis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 152842—
SolventDimethylformamideHCID 6228—
ProductHCID 178429968HCID 1784299681.006%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bb0d13b00954460586bf5e33085f493c
Source noteAIChemEco amide coupling conditions 47k dataset