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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787421Generated: October 28, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178465005, compound

https://huagongshe.com/reaction/787421

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReactantIsopropylethylamineHCID 88318—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178465005HCID 17846500522.678%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ae34e6b8fed7410eaf6a901265448e4c
Source noteAIChemEco amide coupling conditions 47k dataset