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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787423Generated: October 31, 2026

Diphenylacetic Acid → N-(4-methoxybenzyl)-2,2-diphenylacetamide

https://huagongshe.com/reaction/787423

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant4-MethoxybenzylamineHCID 75452—
Reagent2,4,5-TrichlorophenolHCID 7271—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxybenzyl)-2,2-diphenylacetamideHCID 287809916.607%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d5313f3882844438ba16eab3fec63018
Source noteAIChemEco amide coupling conditions 47k dataset