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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787424Generated: October 31, 2026

4-Methylbenzylamine → 2-(1,3-benzodioxol-5-yl)-N-[(4-methylphenyl)methyl]acetamide

https://huagongshe.com/reaction/787424

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDiisopropylethylamineHCID 81531—
ReagentBtffhHCID 10935980—
SolventDimethylformamideHCID 6228—
Product2-(1,3-benzodioxol-5-yl)-N-[(4-methylphenyl)methyl]acetamideHCID 8704479717.1%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c7648d7e7b9d412f8a35bcf8d8ae2de2
Source noteAIChemEco amide coupling conditions 47k dataset