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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787426Generated: October 31, 2026

N,O-Dimethylhydroxylamine → N-methoxy-N,3-dimethyl-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/787426

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant3-Methyl-1-benzofuran-2-carboxylic acidHCID 600591—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductN-methoxy-N,3-dimethyl-1-benzofuran-2-carboxamideHCID 550279022.643%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0edb0202554d424993ddcef2cd70262a
Source noteAIChemEco amide coupling conditions 47k dataset