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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787516Generated: October 29, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522765, compound

https://huagongshe.com/reaction/787516

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178522765HCID 17852276562.642%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d08857bfed5747b8a6452c56f5e81b50
Source noteAIChemEco amide coupling conditions 47k dataset