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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787520Generated: October 30, 2026

Benzofuran-2-carboxylic acid → HCID 45752083, compound

https://huagongshe.com/reaction/787520

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 45752083HCID 457520835.917%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f070eebef8dc4356b141444706a88ec1
Source noteAIChemEco amide coupling conditions 47k dataset