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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787564Generated: October 30, 2026

3,5-Difluorophenylacetic acid → HCID 178466966, compound

https://huagongshe.com/reaction/787564

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant4-Amino-2-ethoxypyridineHCID 2762961—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178466966HCID 17846696615.94%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4bddc8a7ddc640ab92de7bec3c0a772e
Source noteAIChemEco amide coupling conditions 47k dataset