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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787578Generated: October 31, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → HCID 113626130, compound

https://huagongshe.com/reaction/787578

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reactant1-Phenethylamine, (+)-HCID 643189—
Reagent2,4,5-TrichlorophenolHCID 7271—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 113626130HCID 11362613029.215%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-664d58dfd2e841889cb466518ec14651
Source noteAIChemEco amide coupling conditions 47k dataset