反应详情

Scheme 3 illustrates the conversion of 2,2-dinitro 1,3-propanediol cyclic sulfate into 3-azido 2,2-dinitropropanol. First, 2,2-dinitro 1,3-propanediol cyclic sulfate is reacted with sodium azide and dimethylformamide (“DMF”) to open the cyclic sulfate and form sodium 3-azido-2,2-dinitropropyl sulfate. After the cyclic sulfate is opened, the sodium 3-azido-2,2-dinitropropyl sulfate is reacted with 20% sulfuric acid to form 3-azido-2,2-dinitropropanol.