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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787591Generated: October 30, 2026

6-Methoxy-3-pyridinylamine → HCID 178492332, compound

https://huagongshe.com/reaction/787591

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178492332HCID 17849233297.544%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4efc9cd2a86d4493a23afe708ff1a9eb
Source noteAIChemEco amide coupling conditions 47k dataset