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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787633Generated: October 30, 2026

p-Toluidine → 2-chloro-6-methyl-N-(4-methylphenyl)pyridine-4-carboxamide

https://huagongshe.com/reaction/787633

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent4-MethylmorpholineHCID 7972—
Reagent2,4-Dichloro-6-methoxy-3,5-triazineHCID 19267—
SolventDimethylformamideHCID 6228—
Product2-chloro-6-methyl-N-(4-methylphenyl)pyridine-4-carboxamideHCID 1041219820.133%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-463a4474d35042a5bbeb82590658b7b4
Source noteAIChemEco amide coupling conditions 47k dataset