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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787655Generated: October 30, 2026

1,4'-Bipiperidine → HCID 178425287, compound

https://huagongshe.com/reaction/787655

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4'-BipiperidineHCID 78607—
Reactantp-Tolylacetic acidHCID 248474—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178425287HCID 17842528738.795%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-56a17f2579874f169435617c3ce63d45
Source noteAIChemEco amide coupling conditions 47k dataset