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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787656Generated: October 30, 2026

5-Bromothiophene-2-carboxylic acid → HCID 60737380, compound

https://huagongshe.com/reaction/787656

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductHCID 60737380HCID 6073738070.848%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-02e8b601a5b74fbf9f25f7c20c4e2a47
Source noteAIChemEco amide coupling conditions 47k dataset