HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 78769Generated: October 27, 2026
Hydrogen Peroxide → 3-Fluoroisonicotinic acid 1-oxide
https://huagongshe.com/reaction/78769
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | 3-Fluoropyridine-4-carboxylic acid | HCID 345361 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-Fluoroisonicotinic acid 1-oxide | HCID 57649637 | — |
Reaction Steps
To a solution of 3-fluoroisonicotinic acid (5.0 g, 35.33 mmol) in acetic acid (25 ml) was added hydrogen peroxide (6 ml). The reaction mixture was stirred at 70-80° C. overnight. The solvent was removed to obtain 5.5 g of 3-fluoroisonicotinic acid 1-oxide in quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08841459B2 |
|---|
| Source dataset | uspto-grants-2014_09 |
|---|
| ORD ID | ord-8aad015027a94337b306350cae66a894 |
|---|
| Source note | uspto-grants-2014_09 |
|---|
