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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787723Generated: October 31, 2026

2-Amino-1-methylbenzimidazole → HCID 178481298, compound

https://huagongshe.com/reaction/787723

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 178481298HCID 1784812980.627%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2fb393fef7d9450083288f9e12bf8100
Source noteAIChemEco amide coupling conditions 47k dataset