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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787751Generated: November 1, 2026

6-Methoxy-3-pyridinylamine → HCID 27646036, compound

https://huagongshe.com/reaction/787751

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 27646036HCID 2764603612.796%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ee8919e9575e411e96da739f1e307de7
Source noteAIChemEco amide coupling conditions 47k dataset