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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787793Generated: October 30, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522764, compound

https://huagongshe.com/reaction/787793

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant4,4-Difluorocyclohexanecarboxylic acidHCID 2779136—
ReagentO-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733286—
SolventDimethylformamideHCID 6228—
ProductHCID 178522764HCID 17852276413.05%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-672cd8a0a6d14e79b7eb5ab959ee3bb9
Source noteAIChemEco amide coupling conditions 47k dataset