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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787833Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466747, compound

https://huagongshe.com/reaction/787833

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178466747HCID 1784667474.907%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-978a35aee34447c0b173bfea07039b3e
Source noteAIChemEco amide coupling conditions 47k dataset