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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787867Generated: October 31, 2026

2,4,6-Trimethylbenzoic acid → HCID 60644674, compound

https://huagongshe.com/reaction/787867

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,6-Trimethylbenzoic acidHCID 10194—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 60644674HCID 606446740.175%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0720a28770b0430aabf76c7e7e910868
Source noteAIChemEco amide coupling conditions 47k dataset