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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 78794Generated: October 25, 2026

2-Methoxyphenethylamine → 3-[(2-fluoro-4-iodophenyl)amino]-N-[2-(2-methoxyphenyl)ethyl]isonicotinamide

https://huagongshe.com/reaction/78794

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethoxyphenethylamineHCID 74896—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
Product3-[(2-fluoro-4-iodophenyl)amino]-N-[2-(2-methoxyphenyl)ethyl]isonicotinamideHCID 11656127—

Reaction Steps

3-[(2-fluoro-4-iodophenyl)amino]-N-[2-(2-methoxyphenyl)ethyl]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.54 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.81 mmol of 2-(2-methoxy-phenyl)-ethylamine. LC/MS [10.19 min; 492 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08841459B2
Source datasetuspto-grants-2014_09
ORD IDord-7f26916c38b941baa12726dda92f05e6
Source noteuspto-grants-2014_09